Baycol

• Avoid or limit alcohol
• Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
• Pronsky, Z Food Medication Interactions, 11th edition, 1999
• Avoid grapefruit juice with this medication, it may theoretically interact with the drug.
• Pronsky, Z Food Medication Interactions, 11th edition, 1999
• Lilja JJ, Kivisto KT, Neuvonen PJ. Grapefruit juice increases serum concentrations of atorvastatin and has no effect on pravastatin. Clin Pharmacol Ther 1999; 66:118-27.
• Baycol may deplete Co-Q-10 levels. There are several studies that show the HMG-CoA Reductase Inhibitors inhibit the biosynthesis of Co-Q-10.
• Bargossi AM, Battino M, Gaddi A, et al. Exogenous CoQ10 preserves plasma ubiquinone levels in patients treated with 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors. Int J Clin Lab Res 24: 171-176, 1994.
• Folkers K, et al. Lovastatin decreases coenzyme Q levels in humans. Proc Natl Acad Sci USA 87(22): 8931-8934, 1990.
• Ghirlanda G, et al. Evidence of plasma CoQ10-lowering effect by HMG-CoA reductase inhibitors: a double-blind, placebo-controlled study. J Clin Pharmacol 33(3): 226-229, 1993.
• Mortensen SA, et al. Dose-related decrease of serum coenzyme Q10 during treatment with HMG-CoA reductase inhibitors. Mol Aspects Med 18(Suppl.): S137-S144, 1997.
• Red yeast rice contains ingredients similar to the statin drugs and may have additive effects if used together.
• McKevoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998
• The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 2000
• These herbs have approval status by the German Commission E regarding this specific action (cholesterol lowering): Psyllium seed, blonde Psyllium seed husk.
• Blumenthal, M (Ed.): The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. American Botanical Council. Austin, TX. 1998.
• These herbs have shown hypocholesterolic effects: Artichoke Plant, Fenugreek, Garlic Plant, Plantain. They may have additive effects with Baycol, consult a pharmacist regarding their use together.
• Newall CA, Anderson LA, Phillipson JD. Herbal Medicines A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996
• PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000