Avandia

• Limit or avoid alcohol.
• Graedon J, Graedon T: The People's Guide to Deadly Drug Interactions, 1995
• Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
• Caution with high doses of nicotinic acid as it raises glucose levels .
• Balch, J.F. & Balch, P.A.: Prescription for Nutritional Healing. Second Edition. Avery, New York. 1996.
• Schwartz ML. Severe reversible hyperglycemia as a consequence of niacin therapy. Arch Intern Med. 1993 Sep 13;153(17):2050-2.
• The supplement ipriflavone may increase the blood levels of oral antidiabetic agents. This could cause blood sugar to fall dangerously low. Consult a physician before taking ipriflavone with oral hypoglycemic agents.
• Monostory K, et al. Ipriflavone as an inhibitor of human cytochrome P450 enzymes. Br J Pharmacol 123(4): 605-610, 1998.
• These supplements may reduce blood sugar levels and require a dosage adjustment of Avandia: carnitine, chromium, coenzyme Q10 and vanadium.
• Singh RB, Niaz MA, Rastogi SS, et al. Effect of hydrosoluble coenzyme Q10 on blood pressures and insulin resistance in hypertensive patients with coronary artery disease. J Human Hypertens 13: 203-208, 1999.
• Mingrone G. L-carnitine improves glucose disposal in type 2 diabetic patients. J Am Col Nutr 18: 77-82, 1999.
• Jacob S, Ruus P, Hermann R, et al. Oral administration of RAC-alpha-lipoic acid modulates insulin sensitivity in patients with type-2 diabetes mellitus: a placebo-controlled pilot trial. Free Radic Biol Med 27: 309-314, 1999.
• Cohen N, et al. "Oral vanadyl sulfate improves hepatic and peripheral insulin sensitivity in patients with non-insulin-dependent diabetes mellitus." J Clin Invest, 1995; 95: 2501-509.
• Potatoes can interfere with blood sugar levels and Avandia dosage may require adjustment.
• Gannon MC, et al. Diabetes Care 1993;16:874.
• The Review of Natural Products, Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
• The bulbs of the common onion plant and common garlic plant, as well as leaves of bilberry and blueberry have significant oral hypoglycemic action. Hypoglycemic medications may require adjustment.
• Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
• Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996
• Mathew PT and Augusti KT. Hypoglycaemic effects of onion, Allium cepa Linn. on diabetes mellitus, a preliminary report. Indian J Physiol Pharmacol 19: 213-217, 1975
• These herbs may reduce blood sugar levels and therefore require an adjustment in the dosage of Avandia: : bitter melon, burdock, dandelion, fenugreek, ginseng, and gymnema.
• Akhtar MS. Trial of Momordica charantia Linn (Karela) powder in patients with maturity-onset diabetes. J Pak Med Assoc 32: 106-107, 1982.
• Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
• Yaniv Z, Dafni A, Friedman J, et al. Plants used for the treatment of diabetes in Israel. J Ethnopharmacol 19(2): 145-151, 1987.
• Bever BO and Zahnd GR. Plants with oral hypoglycemic action. Q J Crude Drug Res 17: 139-196, 1979.
• Welihinda J, et al. Effect of Momordica charantia on the glucose tolerance in maturity onset diabetes. J Ethnopharmacol 17: 277-282, 1986
• Boden G, et al. Effects of vanadyl sulfate on carbohydrate and lipid metabolism in patients with non-insulin-dependent diabetes mellitus. Metabolism 45: 1130-1135, 1996