RNAgent’s Drug Interaction Database indexes and lists prescription drugs and their interactions with herbal supplements. Search by letter or keyword to find a prescription drug and its interactions with herbal and natural ingredients.
Augmentin
- Consume adequate amounts of fluids, unless otherwise directed.
- Welling PG, Huang H, Koch PA, et al. Bioavailability of ampicillin and amoxicillin in fasted and non-fasting subjects. J Pharm Sci. 1977; 66:549-552.
- Augmentin may hinder the production of B vitamins and vitamin K in the intestine. Supplementation may be beneficial with long term use of the drug.
- Mindell, E, Hopkins V: Prescription Alternatives. New Canaan, CT: Keats Publishing, Inc, 1998; p. 336.
- Hill MJ: Intestinal flora and endogenous vitamin synthesis, Eur J Cancer Prev, 1997, 6 (Suppl 1): S43-5.
- Deguchi Y, et al: Comparative studies on synthesis of water-soluble vitamins among human species of Bifidobacteria, Argic Biol Chem, 1985, 19 (1): 13-19.
- Conly J and Stein K: Reduction of vitamin K2 concentrations in human liver associated with the use of broad spectrum antimicrobials, Clin Invest Med, 1994, 17 (6):531-9.
- Antibiotics kill bacteria, including beneficial flora in the gut, which may affect digestion and/or elimination. Supplementation with acidophilus or bifidus may aid in restoring this beneficial flora.
- Bengmark S & Gianotti L: Nutritional support to prevent and treat multiple organ failure. World J Surg, 1996 May, 20:4, 474-81.
- Fuller R. Probiotics in human medicine. Gut 1991;32:439-42 [review].
- Elmer GW, Surawicz CM, McFarland LV. Biotherapeutic agents. A neglected modality for the treatment and prevention of selected intestinal and vaginal infections. JAMA 1996;275:870-76.
- Cummings JH, Macfarlane G: Role of intestinal bacteria in nutrient metabolism, JPEN J Parenter Enteral Nutr, 1997, 21(6): 357-65.
- Gorbach SL: Bengt E. Gustafsson Memorial Lecture, Function of the Normal Human Microflora, Scand J Infect Dis Suppl, 1986, 49:17-30.
- Bromelain may increase absorption of Augmentin.
- Neuvonen PJ et al., Comparative effect of food on absorption of ampicillin and pivampicillin. J Int Med Res 1977; 5: 71-76.
- Tinozzi S, Venegoni A. Effect of bromelain on serum and tissue levels of amoxicillin. Drugs Exp Clin Res 1978;4:39-44.
- Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998