Aspirin

• Aspirin increases urinary excretion of vitamin C. Decreased vitamin status with respect to vitamin C as well as folate have been noted.
• Pronsky, Z Food Medication Interactions, 11th edition, 1999.
• McKevoy GK, ed. AHFS Drug Information. Bethesda MD: American Society of Health-System Pharmacists, 1998
• Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
• Coffey G, Wilson CWM. Ascorbic acid deficiency and aspirin induced haematemesis. BMJ 1975; I: 208.
• Buist RA. Drug-nutrient interactions: an overview. Intl Clin Nutr Rev 1984;4(3):114 .
• Take with food or milk to decrease stomach upset
• Pronsky, Z Food Medication Interactions, 11th edition, 1999
• Avoid alcohol.
• Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
• Pronsky, Z Food Medication Interactions, 11th edition, 1999
• May cause glucose level changes, caution with diabetes
• Pronsky, Z Food Medication Interacations, 11th edition, 1999
• Taking vitamin E together with aspirin has been associated with bleeding problems.
• Liede KE, Haukka JK, Saxn LM, Heinon OP. Increased tendency towards gingival bleeding caused by joint effect of alpha-tocopherol supplementation and acetylsalicylic acid. Ann Med 1998;30:542-46.
• The use of over three grams of aspirin has been associated with zinc depletion.
• Ambanelli U, Ferraccioli GF, Serventi G, Vaona GL. Changes in serum and urinary zinc induced by ASA and indomethacin. Scand J Rheumatol 1982;11:63-64
• The antithrombotic effect of garlic plant, ginger, ginkgo or onion plant may be increased by concomitant administration of salicylates like aspirin.
• Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996
• Pronsky, Z Food Medication Interactions, 11th editon, 1999
• Rosenblatt M, Mindel . Spontaneous hyphema associated with ingestion of Ginkgo biloba extract. J N Eng J Med 1997; 336: (15):1108
• Rowin J, Lewis SL. Spontaneous bilateral subdural hematomas associated with chronic Ginkgo biloba ingestion. Neurology 1996;46:1775-6.
• Licorice root reduces aspirin absorption and protects gastric mucosa against aspirin toxicity
• Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
• Rees WDW, Rhodes J, Wright JE, et al. Effect of deglycyrrhizinated liquorice on gastric mucosal damage by aspirin. Scand J Gastroenterol 1979;14:605-7.
• Due to presence of salicylates in meadowsweet, poplar and white willow, it may potentiate the effects of other anticoagulant agents, such as aspirin, and heparin.
• Facts and Comparisons, Review of Natural Products, Wolters Kluwer Company, 2000.
• Janssen PL: Acetylsalicylate and salicylates in foods. Cancer Lett, 1997 Mar, 114:1-2, 163-4.