RNAgent’s Drug Interaction Database indexes and lists prescription drugs and their interactions with herbal supplements. Search by letter or keyword to find a prescription drug and its interactions with herbal and natural ingredients.
Alora
- Studies have shown that grapefruit juice significantly increases estradiol levels in the blood. Do not drink grapefruit juice or eat grapefruit while taking this medication.
- Schubert W, Cullberg G, Edgar B, Hedner T. Inhibition of 17 beta-estradiol metabolism by grapefruit juice in ovariectomized women. Maturitas 1994;20:155-63.
- Schubert W, Eriksson U, Edgar B, et al. Flavonoids in grapefruit juice inhibit the in vitro hepatic metabolism of 17 beta-estradiol. Eur J Drug Metab Pharmacokinet 1995;3:219-24.
- Weber A, Jager R, Borner A, et al. Can grapefruit juice influence ethinylestradiol bioavailability? Contraception 1996;53:41-7.
- It may also be possible that supplements containing quercetin also increase the levels of estradiol in the blood. Talk to your pharmacist if you are taking any supplements that contain this nutrient.
- Kuiper GG, Lemmen JG, Carlsson B, et al. Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta. Endocrinology 1998;139:4252-63.
- This drug may increase risk of folic acid deficiency, which could affect reproductive and cardiovascular health. Supplementation is considered beneficial.
- Kornberg A, Segal R, Theitler J, et al: Folic acid deficiency, megaloblastic anemia and peripheral polyneuropathy due to oral contraceptives, Isr J Med Sci, 1989, 25 (3): 142-5.
- Harper JM, Levine AJ, Rosenthal DL, et al: Erythrocyte folate levels, oral contraceptive use and abnormal cervical cytology, Acta Cytol, 1994, 38 (3): 324-30.
- Vitamin C may result in increased estrogen effects.
- Blum M, Kitai E, Ariel Y, Et Al: Oral Contraceptive Lowers Serum Magnesium, Harefuah, 1991, 121 (10):363-4.
- The following herbs may affect hormone levels: Agnus Castus (Vitex), Alfalfa, Bayberry, Black Cohosh, Dong Quai, Ginseng, Horseradish, Licorice Root, Pleurisy Root, Red Clover, Red Sage, Saw Palmetto, Tobacco, Vervain, and Wild Yam. Consult your pharmacist for more information.
- Newall CA, Anderson LA, Phillipson JD. Herbal Medicines A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996.
- Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998