Accupril

• Avoid consuming excessive potassium in foods and supplements while taking Accupril. Ask your physician or pharmacist for more information about electrolyte balance.
• Burnakis TG & Mioduch HJ: Combined therapy with captopril and potassium supplementation. A potential for hyperkalemia. Arch Intern Med 1984; 144:2371-2372.
• Good CB, McDermott L, McCloskey B. Diet and serum potassium on ACE inhibitors. JAMA 1995;274:538.
• Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
• The use of alcohol should be limited.
• Pronsky, ZM: Food-Medication Interactions, 11th edition, 1999
• Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
• Accupril may contribute to zinc deficiency with long term use. Discuss the need for supplementation with a pharmacist.
• Golik A, Zaidenstein R, Dishi V, et al: Effects of captopril and enalapril on zinc metabolism in hypertensives, J Am Coll Nutr, 1998, 17(1):75-8.
• Golik A, Modai D, Averbukh Z, et al: Zinc metabolism in patients treated with captopril versus enalapril, Metabolism, 1990, 39(7): 665-7.
• Some herbs possess cardiac activity and they may interact with Accupril to increase side effects: black hellebore, calamus, cereus, cola, coltsfoot, devil's claw, European mistletoe, fenugreek, fumitory, digitalis leaf, hedge mustard, figwort, lily of the valley roots, motherwort, pleurisy root, squill bulb leaf scales, white horehound, mate, scotch broom flower, shepherd's purse, and wild carrot
• Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996.
• The Review of Natural Products, Clinisphere 2.0, Wolters Kluwer Company, 2000
• Blumenthal M, et al. ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
• PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
• Avoid natural licorice products, Ginseng, and Ephedra (Ma huang) which may interfere with antihypertensive therapy.
• Pronsky, ZM: Food-Medication Interactions, 11th edition, 1999
• Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
• These herbs may possess diuretic properties which could result in additive effects with accupril. They include: Alfalfa, Angelica, Astragalus, Basil, Bean Pod, Buckthorn, Burdock, Butchers Broom, Buchu, Celery, Cleavers, Dandelion, Elecampane, Elder, Goat's Rue, Hempnettle, Horsetail, Indian-Hemp, Juniper, Marigold, Meadowsweet, Parsley, Rauwolfia, Sarsaparilla, Sweet clover, Turmeric, and Vervain
• PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
• Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996.
• Blumenthal M, et al. ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.